Express Scripts 100 Over 100 Initiative

Archon Genomics X Prize Presented by Express Scripts

The Archon Genomics X PRIZE presented by Express Scripts® is an initiative for scientific teams to rapidly, accurately and economically sequence 100 whole human genomes – the 6 billion bases that make up the DNA within the 46-chromosome diploid genome in each human cell – to a level of accuracy never before achieved. The result will be the world's first "medical grade” genome, a critically needed clinical standard that will transform genomic research into usable medical information to improve patient diagnosis and treatment. This groundbreaking global competition will inspire breakthrough genome sequencing innovations and technologies that will accelerate a new era of personalized, genomics-based medicine.

The 100 human genomes to be sequenced in this competition will be donated by 100 centenarians (ages 100 or older) from all over the world. This group of vital centenarians is known as the Medco 100 Over 100. Sequencing the genomes of the Medco 100 Over 100 presents an unprecedented opportunity to identify those "rare genes" that protect against diseases, while giving researchers valuable clues to health and longevity. These centenarians’ genes are providing us with a window to the past that may significantly impact the future of healthcare.

The knowledge gained by compiling and comparing this library will further our understanding of health and longevity. Decoding the secrets to a long life may lead to radical medical breakthroughs to the benefit of humanity.

For more public information about the Archon Genomics X PRIZE presented by Express Scripts, please visit: http://genomics.xprize.org/

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